GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs1577917 | 1 | rs35761942 | chr6:86629504 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.57 | 1.33E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs35797755 | chr6:86706554 | SNHG5 | chr6:86386726-86388451:- | -0.52 | -9.13 | 4.08E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs2243480 | 1 | rs35820085 | chr7:65442758 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.47 | 1.05E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs35825738 | chr7:65318027 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.39 | 1.49E-5 | Diabetic kidney disease |
| BLCA | cis | rs7927771 | 1 | rs35902101 | chr11:47795169 | C1QTNF4 | chr11:47611216-47615961:- | -0.3 | -5.65 | 3.22E-8 | Subjective well-being |
| BLCA | cis | rs12908161 | 1 | rs35960805 | chr15:85343980 | LOC388152 | chr15:84867600-84898920:- | -0.23 | -4.16 | 4.0E-5 | Schizophrenia |
| BLCA | cis | rs12748152 | 1 | rs35962879 | chr1:27283456 | GPN2 | chr1:27205873-27216869:- | 0.47 | 4.05 | 6.12E-5 | HDL cholesterol;Triglycerides;LDL cholesterol |
| BLCA | cis | rs2243480 | 1 | rs36033484 | chr7:65390558 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.47 | 1.02E-5 | Diabetic kidney disease |
| BLCA | cis | rs12908161 | 1 | rs36033486 | chr15:85319692 | LOC388152 | chr15:84867600-84898920:- | -0.23 | -4.18 | 3.68E-5 | Schizophrenia |
| BLCA | cis | rs9487094 | 1 | rs36035949 | chr6:109736614 | SMPD2 | chr6:109761931-109765121:+ | 0.21 | 3.98 | 8.34E-5 | Height |
| BLCA | cis | rs2243480 | 1 | rs36068983 | chr7:65408991 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.47 | 1.02E-5 | Diabetic kidney disease |
| BLCA | cis | rs1577917 | 1 | rs36096931 | chr6:86693134 | SNHG5 | chr6:86386726-86388451:- | -0.49 | -8.73 | 7.95E-17 | Response to antipsychotic treatment |
| BLCA | cis | rs60843830 | 1 | rs36216559 | chr2:262335 | SH3YL1 | chr2:218138-264810:- | -0.45 | -11.68 | 3.7E-27 | Spherical equivalent (joint main effects and education interaction) |
| BLCA | cis | rs9457247 | 1 | rs364283 | chr6:167383750 | RNASET2 | chr6:167343008-167412795:- | -0.23 | -4.95 | 1.14E-6 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs364451 | chr6:167384756 | RNASET2 | chr6:167343008-167412795:- | -0.23 | -4.86 | 1.7E-6 | Crohn's disease |